Research Article

[Retracted] Preventive Effects of Mandarin Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin on Acetaminophen-Induced Hepatonephrotoxicity in Wistar Rats

Table 4

Effect of MPHE, hesperidin, and quercetin on serum TNF-α and IL-4 levels of NAPAP-administered rats.

GroupsParameter
TNF-α (pg/ml)% changeIL-4 (U/L)% change

Normal
NAPAPa295.60a-67.82
NAPAP+MPHEb-24.11b136.14
NAPAP+hesperidinbc-30.95b128.75
NAPAP+quercetinc-41.63b135.39

Data are expressed as . The number of animals in each group is 6. aSignificant at in comparison with the normal values. bSignificant at in comparison with NAPAP values. cSignificant at in comparison with NAPAP+MPHE values. Percentage changes are calculated by comparing NAPAP-administered control with normal control and NAPAP-administered treated rats with NAPAP-administered control.