Research Article

[Retracted] Preventive Effects of Mandarin Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin on Acetaminophen-Induced Hepatonephrotoxicity in Wistar Rats

Table 5

Effect of MPHE, hesperidin, and quercetin in liver content of GSH and activities of GPx and GST and SOD and LPO in NAPAP-administered rats.

Parameter groupsLPO (nmole/100 mg tissue)% changeSOD (U/g tissue)% changeGSH (nmole/100 mg tissue)% changeGPx (mU/100 mg tissue)% changeGST (U/100 mg tissue)% change

Normal
NAPAPa113.10a-34.55a-34.31a-8.49a-25.81
NAPAP+MPHEb-37.20bc45.75b41.42b7.25b21.08
NAPAP+hesperidinbc-31.30b36.30b43.58b7.26b23.52
NAPAP+quercetinc-24.44bc39.95b49.73b7.59b26.66

Data are expressed as . The number of animals in each group is 6. aSignificant at in comparison with the normal values. bSignificant at in comparison with NAPAP values. cSignificant at in comparison with NAPAP+MPHE values. Percentage changes are calculated by comparing NAPAP-administered control with normal control and NAPAP-administered treated rats with NAPAP-administered control.