Research Article

[Retracted] Preventive Effects of Mandarin Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin on Acetaminophen-Induced Hepatonephrotoxicity in Wistar Rats

Table 6

Effect of MPHE, hesperidin, and quercetin on kidney content of GSH and activities of GPx, GST, and SOD activities as well as LPO level of NAPAP-administered rats.

Parameter groupsLPO (nmol/100 mg tissue)% changeSOD (U/g tissue)% changeGSH (nmol/100 mg tissue)% changeGPx (mU/100 mg tissue)% changeGST (U/100 mg tissue)% change

Normal
NAPAP53.35a-21.35a-31.86a-6.60a-18.07
NAPAP+MPHEb-26.040.59b33.52b4.56b13.31
NAPAP+hesperidinb-19.24b10.64b29.88b5.15b15.02
NAPAP+quercetinb-24.91b19.85b35.29b4.70b12.59

Data are expressed as . The number of animals in each group is 6. aSignificant at in comparison with the normal values. bSignificant at in comparison with NAPAP values. Percentage changes are calculated by comparing NAPAP-administered control with normal control and NAPAP-administered treated rats with NAPAP-administered control.