Upregulated circTMEM59 Inhibits Cell Growth and Metastasis by miR-668-3p/ID4 Axis in Colorectal Cancer

Table 1

Relevance analysis of circTMEM59 and miR-668-3p expression in CRC patients.

Variable	CircTMEM59		value	miR-668-3p		value
	High	Low		High	Low
All cases	50	50		50	50
Age (years)
<60	22	21	0.8395	20	23	0.5446
≥60	28	29		30	27
Gender
Male	28	27	0.8415	26	29	0.5463
Female	22	23		24	21
Tumor size (cm)
<4	35	19	0.0013	20	34	0.0050
≥4	15	31		30	16
TNM staging system
T1 + T2	34	21	0.0090	22	33	0.0270
T3 + T4	16	29		28	17
Tumor stage
Stage I + II	33	18	0.0027	20	31	0.0278
Stage III + IV	17	32		30	19
Lymph node metastasis
No	36	21	0.0025	23	34	0.0263
Yes	14	29		27	16
Distant metastasis
No	42	36	0.1475	38	40	0.6293
Yes	8	14		12	10

and .