Effects of Antioxidant Supplementation on Metabolic Disorders in Obese Patients from Randomized Clinical Controls: A Meta-Analysis and Systematic Review

Table 4

Risk of bias analysis of included trials.

Study	Randomization		Blinding of participants and personnel (performance bias)		Allocation concealment (selection bias)	Integrality of date outcome (attrition bias)	Selective reporting (reporting bias)	Other bias
Caballero [1]	Computer simulation	Random	Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Collaborators et al. [2]	Unclear		Unclear		Unclear	Unclear	Unclear	Unclear
Bazrafshani et al. [3]	Unclear		Single-blind simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Valerio et al. [4]	Unclear		Unclear		Unclear	Unclear	Unclear	Unclear
Malone and Hansen [5]	Computer simulation	Random	Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Nikolopoulou and Kadoglou [6]	Computer simulation	Random	Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Milic et al. [7]	Randomization list		Unclear		Unclear	Unclear	Unclear	Unclear
Fernández-Sánchez et al. [8]	Block size of 4 subjects’ schedule		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Fonseca-Alaniz et al. [9]	Computer simulation	Random	Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Dludla et al. [10]	Unclear		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Bjorklund and Chirumbolo [11]	Computer simulation	Random	Triple-blind simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Ohishi et al. [12]	Blocked size of 4 number tables		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Szulinska et al. [13]	Blocked size of 4 number tables		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Hosseinpour-Arjmand [14]	Computer simulation	Random	Unclear		Unclear	Unclear	Unclear	Unclear
Callcott et al. [15]	Simulation blocked size of 4	Random	Double-blinded	Randomized	Unclear	Unclear	Unclear	Unclear
Zhao et al. [16]	Random number table		Simulation		Unclear	Unclear	Unclear	Unclear
Showell et al. [17]	Unclear		Unclear		Unclear	Unclear	Unclear	Unclear
Emami et al. [18]	Random number table with a permuted block size of two		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Ekhlasi et al. [19]	Unclear		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Shadman et al. [20]	Unclear		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Showell et al. [21]	Unclear		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Smits et al. [22]	Computer simulation		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Piche et al. [23]	Unclear	Random	Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Leisegang et al. [24]	Unclear		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Park et al. [25]	Unclear		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Dostal et al. [26]	Unclear		Unclear		Unclear	Unclear	Unclear	Unclear
Zhang et al. [27]	Unclear		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Farr et al. [28]	Randomization list		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Yadav et al. [29]	Computer simulation	Random	Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear
Balsan et al. [30]	Unclear		Double-blinded simulation	Randomized	Unclear	Unclear	Unclear	Unclear