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| Green synthesis-based nanoparticles | Chemical-based nanoparticles |
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| Plants, seaweeds, seagrasses, and microorganisms are examples of biological sources that are both cost-effective and have fewer negative effects. | Chemical-based NP manufacturing is both costly and detrimental to the environment. |
| Plant-based nanoparticles do not need a lot of pressure, energy, or heat to work and remove harmful chemicals. | At room temperature, most chemical-mediated nanoparticle production procedures are carried out. |
| The key benefit of green synthesis nanoparticles is that they are environmentally beneficial because they use waste materials as a raw supplement in the synthesis process. This technique’s raw resources are all renewable. | Chemical-mediated synthesis of nanoparticles has the fundamental advantage of allowing the manufacture of particles with defined size, dimension, composition, and structure, which can be applied in a variety of study areas. |
| Nanoparticle synthesis from terrestrial plants is a relatively simple process since it eliminates the need to change the liquid medium. To make silver NPs, aqueous plant extracts of Matricaria recutita were employed. | Silver NPs were synthesized at 55–60°C using two stabilizing agents, polyvinylpyrrolidone (PVP), and gelatin, using various sugars such as glucose, fructose, lactose, and sucrose. |
| These nanoparticles range in size from a few nanometers to around 100 nanometers. | These nanoparticles range in size from 25 to 450 nanometers. |
| Low yield is the fundamental drawback of green nanoparticle synthesis. | Chemical-based nanoparticle can induce inhalation issues and a variety of deadly diseases due to their minuscule size. |
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