Research Article

α-Lipoic Acid Strengthens the Antioxidant Barrier and Reduces Oxidative, Nitrosative, and Glycative Damage, as well as Inhibits Inflammation and Apoptosis in the Hypothalamus but Not in the Cerebral Cortex of Insulin-Resistant Rats

Figure 1

The outline of the experiment. CD ALA-: control animals not supplemented with ALA; HFD ALA-: high-fat diet-fed animals not supplemented with ALA; CD ALA+: control animals supplemented with ALA; HFD ALA+: high-fat diet-fed animals supplemented with ALA; NaCl: intragastric administration of saline; ALA: intragastric administration of α-lipoic acid.