Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK

<div>The effect of Dex on oxidative stress and apoptosis. (a–c) The level of oxidative stress. (d) The relative expression of cleaved caspase-3, cleaved caspase-9, Bax, and antiapoptotic protein Bcl-2 in SN of mice was studied using the western blot technique. (g, h) Densitometry analysis of proteins. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK 