Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK

<div>The effect of Dex on mitochondrial function. (a–d) Dex-mediated alterations on mitochondrial Complexes I-IV. (e) Relative expression of Mfn2 and Drp1 in SN of mice was studied using the western blot technique. (g, f) Densitometry analysis of proteins. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK 