Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK

<div>Dex regulated the expression of p-AMPK, PINK1, and Parkin. (a) The expression of AMPK, p-AMPK, PINK1, and Parkin was analyzed by western blot. (b–f) Densitometric quantification of AMPK, p-AMPK, PINK1, and Parkin. 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK 