Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2

<div>Se activated the Nrf2 signaling pathway in TBHP-exposed NPCs. (a, b) Representative western blot bands and quantitation of the expression of Nrf2 and HO-1 in NPCs. (c) Nucleus translocation and expression level of Nrf2 in NPCs (scale bar: 50 <i>μ</i>m). (d, e) Representative western blot bands and quantitation of the expression levels of Nrf2, HO-1, and SOD2 in NPCs treated with ML385 and Se. (f) Nuclear translocation and expression level of Nrf2 in NPCs treated with or without ML385 (scale bar: 50 <i>μ</i>m). 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2 

Figure 5 | Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2 