Research Article
Specific PFKFB3 Inhibitor Memorably Ameliorates Intervertebral Disc Degeneration via Inhibiting NF-κB and MAPK Signaling Pathway and Reprogramming of Energy Metabolism of Nucleus Pulposus Cells
Figure 1
Effects of KAN0438757 (KAN) on the cytotoxicity and proliferation of nucleus pulposus primary (NPP) cells in vitro. (a) The chemical structure of KAN. (b) Cell viability of KAN-treated NPPs was tested by CCK-8 at 24 hours. (c–f) Cell proliferation effect of NPPs treated by negative control or different concentrations KAN was tested by CCK-8 at 24, 48, 72, and 96 hours. Data are expressed as , . ns: no significance.
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