Naringin protects human nucleus pulposus cells against TNF-α-induced inflammation, oxidative stress, and loss of cellular homeostasis by enhancing autophagic flux via AMPK/SIRT1 activation

Figure 1

Effect of naringin on TNF-α-induced human NP cells. (a) Chemical structure of naringin. (b) Identification of human NP cell marker CD24 by flow cytometry. (c) CCK-8 results of human NP cells treated with different concentrations of naringin contain 0.1% DMSO for 24 h. (d) CCK-8 results of naringin pretreated human NP cells induced by TNF-α for 24 h. The data represent the . Significant differences between groups are indicated as , , and , .

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