Naringin protects human nucleus pulposus cells against TNF-<i>α</i>-induced inflammation, oxidative stress, and loss of cellular homeostasis by enhancing autophagic flux via AMPK/SIRT1 activation

<div>AMPK signaling is involved in naringin-triggered activation of autophagy in human NP cells. (a) The protein expressions of p-AMPK/AMPK were measured by Western blotting. (b) The protein levels of LC3, Beclin-1, and P62 were measured by Western blotting. 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Oxidative Medicine and Cellular Longevity

fig8

Figure 8

Figure 8: Naringin protects human nucleus pulposus cells against TNF-<i>α</i>-induced inflammation, oxidative stress, and loss of cellular homeostasis by enhancing autophagic flux via AMPK/SIRT1 activation 

Figure 8 | Naringin protects human nucleus pulposus cells against TNF-α-induced inflammation, oxidative stress, and loss of cellular homeostasis by enhancing autophagic flux via AMPK/SIRT1 activation 