Perspectives on the Molecular Mediators of Oxidative Stress and Antioxidant Strategies in the Context of Neuroprotection and Neurolongevity: An Extensive Review

Figure 3

Monosialotetrahexosyl ganglioside-incorporated reconstituted high-density lipoprotein (GM1-rHDL) possesses antibody-like high binding affinity to Aβ, facilitates Aβ degradation by microglia and Aβ efflux across the blood-brain barrier (BBB), and simultaneously allows the efficient loading of neuroprotective agents, serving as a nanoparticulate drug delivery system for the combination therapy of AD [155].