TXNIP: A Double-Edged Sword in Disease and Therapeutic Outlook

Figure 5

The main mechanism of TXNIP in the brain and nervous system diseases. TXNIP: thioredoxin-interacting protein; TRX: thioredoxin; NLRP3: NOD-like receptor family protein 3; Nrf2: nuclear factor erythrocyte 2-related factor 2; DI-NBP: Dl-3-n-butylphthalide.