Bradykinin and Galectin-3 in Survived and Deceased Patients with COVID-19 Pneumonia: An Increasingly Promising Biochemical Target

Table 6

COX regression analysis of predictors of factors associated with mortality in patients with COVID-19 confirmed pneumonia.

Variables	Hazard ratio (95% CI)	value	Adjusted hazard ration (95% CI)	value
Age above 50 years	1.01 (1.00-1.02)	0.001	1.588 (1.131-2.227)	0.006
Duration from first symptom to admission	1.22 (1.17-1.26)	0.001	2.488 (1.865-3.432)	0.001
mg/dl	1.47 (1.16-1.83)	0.002	0.835 (0.635-1.097)	0.187
D-dimer elevated	1.87 (1.32-2.55)	0.001	1.33 (0.857-1.722)	0.071
CRP elevated	1.63 (1.11-2.32)	0.001	1.45 (0.951-1.804)	0.152
Lymphocyte count elevated	0.74 (0.59-0.94)	0.011	0.531 (0.242-0.511)	0.001
Monocyte count decreased	1.01 (1.01-1.01)	0.001	1.12 (0.880-1.323)	0.259
Hypertension presence	2.33 (1.89-3.01)	0.001	1.801 (0.746-1.606)	0.072
Diabetes presence	1.45 (1.15-1.73)	0.001	0.935 (0.655-1.101)	0.134
Bradykinin above 200000 ng/ml	1.001 (1.001-1.001)	0.001	2.135 (1.666-2.567)	0.001
Galectine-3 above	1.07 (1.04-1.016)	0.001	1.182 (0.991-1.651)	0.244