Research Article

AdipoR1 Regulates Ionizing Radiation-Induced Ferroptosis in HCC cells through Nrf2/xCT Pathway

Figure 2

AdipoR1 knockdown increased radiosensitivity of HCC cells. (a and d) AdipoR1 knockdown was determined by Western blot in MHCC-97H (a) and HepG2 (d) cells. (b–f) After knockdown of AdipoR1, sensitization of radiation-treated MHCC-97H (b and c) and HepG2 (e and f) cells was evaluated through colony formation assay, respectively. The sensitization of radiation was measured using the multitarget, single-hit model. Data is presented as . , , and .