Research Article
Liensinine Inhibits Osteosarcoma Growth by ROS-Mediated Suppression of the JAK2/STAT3 Signaling Pathway
Figure 5
NAC reversed the effects of liensinine on ROS production, GSSG/GSH imbalance, and MMP loss in osteosarcoma cells. (a, b) The ROS production in SaOS-2 and 143B cells after being treated with NAC and liensinine was detected by FCM. (c, d) The concentrations of GSH and GSSG, as well as the GSSG/GSH rate in SaOS-2 and 143B cells after being treated with NAC and liensinine, were detected by colorimetry. (e, f) The MMP of SaOS-2 and 143B cells after being treated with NAC and liensinine was detected by JC-1 staining. in each group. and vs. control; ^, ^^, and ^^^ vs. NAC; ## and ### vs. liensinine.
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