Electroacupuncture Attenuated Anxiety and Depression-Like Behavior via Inhibition of Hippocampal Inflammatory Response and Metabolic Disorders in TNBS-Induced IBD Rats

Figure 4

EA at ST36 and SP6 altered metabolism in the hippocampus (/group). (a)–(c) PLS-DA scatter plot results of metabolites. (d) and (e) Validation model plot. (f) and (g) Differential metabolites between the control and TNBS group, and the TNBS and group, respectively. Data were shown as , , , by the independent sample test. (h) Venn diagrams demonstrate the number of altered metabolites between the control and TNBS group, the TNBS and group, and the control vs. TNBS (blue) and TNBS vs. group (pink). (i) The differential of meaningful metabolic pathways among the control, TNBS, and group.

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