Glycyrrhizin Attenuates Hypoxic-Ischemic Brain Damage by Inhibiting Ferroptosis and Neuroinflammation in Neonatal Rats via the HMGB1/GPX4 Pathway

Figure 3

Glycyrrhizin ameliorates HIBD-induced mitochondrial injury and oxidative stress. (a) Representative TEM images of neurons and mitochondria in neurons in the injured cortex. (b)–(g) The level of MDA and the activity levels of CAT, GSH, SOD Mn-SOD, and Cu/Zn-SOD in different groups (). (h) Representative images of DHE (red) staining in cortical neuronal cells. (i)–(k) The levels of GSH, SOD, and MDA in vitro (). , vs. the Con group; # vs. the HI group or OGD group.

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