Research Article
Dapagliflozin Ameliorates the Formation and Progression of Experimental Abdominal Aortic Aneurysms by Reducing Aortic Inflammation in Mice
Figure 4
Dapagliflozin treatment reduced MMP2 and MMP9 expression levels. (a) Representative immunostaining images of MMP2 and MMP9 in aortae of PPE-infused mice treated with dapagliflozin or vehicle. (b) and (c) Quantification of MMP2 and 9 expression levels (mean and SD) in aneurysmal aorta. One-way ANOVA analysis was conducted. vs. vehicle. DAPA: dapagliflozin; NS: not significant.
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