MicroRNA-299a-5p Protects against Spinal Cord Injury through Activating AMPK Pathway

<div>The miR-299a-5p agomir inhibits SCI-induced inflammation and NLRP3 inflammasome. (a) MPO activity in the spinal cord from mice treated with the miR-299a-5p agomir or agomir-NC. (b) IL-6 and TNF-<i>α</i> levels in the spinal cord. (c) Western blot images and quantification of p65 phosphorylation. (d) Relative NF-<i>κ</i>B transcriptional activity. (e) Western blot images and quantification of NLRP3, ASC, and casp1 p10. (f) Relative casp1 activity. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: MicroRNA-299a-5p Protects against Spinal Cord Injury through Activating AMPK Pathway 