Electroacupuncture Enhances Neuroplasticity by Regulating the Orexin A-Mediated cAMP/PKA/CREB Signaling Pathway in Senescence-Accelerated Mouse Prone 8 (SAMP8) Mice

Figure 10

EA at 10 Hz improves hippocampal neuroplasticity in SAMP8 mice to alleviate learning and memory deficits. Inhibition of OxA expression promotes the expression of cAMP/PKA/CREB signaling pathway-related proteins, thus improving the synaptic plasticity of glutamate neurons and reversing learning and memory deficits.