Inhibition of PFKFB Preserves Intestinal Barrier Function in Sepsis by Inhibiting NLRP3/GSDMD

Figure 4

Effect of 3PO and Gsdmd gene knockout on inflammatory cytokines in intestinal tissue. (a–c) Levels of IL-6, TNF-α, and IL-1β in small intestinal tissues were measured by ELISA. The values were shown as (). versus sham group; ^### versus CLP group. The values were shown as (). Statistical analysis was performed using a -test (a–c). compared with the no-treatment group and ^## compared with the CLP treatment group.

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