[Retracted] Aquaporin 4 Depolarization-Enhanced Transferrin Infiltration Leads to Neuronal Ferroptosis after Subarachnoid Hemorrhage in Mice

Figure 6

The mechanism of AQP4 involvement in early brain injury after SAH. In the early stage of SAH, transient disturbance of microcirculation and transferrin induced neuronal oxidative stress and iron uptake, leading to neuronal ferroptosis. Overexpression of AQP4 can improve SAH-induced AQP4 depolarization and transferrin infiltration and thus improve neuronal ferroptosis and neurological dysfunction.