miR-409-3p Regulated by GATA2 Promotes Cardiac Fibrosis through Targeting Gpd1

Figure 1

miR-409-3p expression is upregulated in cardiac fibrosis. (a) Dysregulated miRNAs in heart tissues of post-MI mice versus sham mice whose roles in cardiac fibrosis are unknown (). (b) miR-409-3p expression of post-MI mice versus sham mice determined by qRT-PCR (). (c, d) Protein levels of fibrotic biomarkers and miR-409-3p expression in two cell models of cardiac fibrosis induced by Ang II or TGF-β (). and versus respective controls.

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