Oxidative Medicine and Cellular Longevity / 2022 / Article / Tab 1 / Research Article
[Retracted] Two Myricetin-Derived Flavonols from Morella rubra Leaves as Potent α -Glucosidase Inhibitors and Structure-Activity Relationship Study by Computational Chemistry Table 1 Chemical structures of 26 natural flavonols tested in this study.
No. Flavonols Synonyms M.W. R3 R4 R5 R3 R5 R7 R8 IC50 (μ M) 1 Myricetin-3-O -rhamnoside Myricitrin 464.38 OH OH OH Rhamnoside OH H H 2 Myricetin-3-O -(2O -galloyl)-α -L -rhamnoside — 616.10 OH OH OH (2α -L -rhamnoside OH H H 3 Myricetin-3-O -(4O -galloyl)-α -L -rhamnoside — 616.10 OH OH OH (4α -L -rhamnoside OH H H 4 Quercetin-3-O -galactoside Hyperoside 464.40 OH OH H Galactoside OH H H 5 Quercetin-3-O -glucoside Isoquercitrin 464.40 OH OH H Glucoside OH H H 6 Quercetin-3-O -rhamnoside Quercitrin 448.40 OH OH H Rhamnoside OH H H 7 Myricetin-3-O -galactoside — 480.40 OH OH OH Galactoside OH H H 8 Quercetin-3-α -L -arabinofuranoside Avicularin 434.30 OH OH H Arabinoside (furan type) OH H H 9 Quercetin-3-α -L -arabinopyranoside Guaijaverin 434.30 OH OH H Arabinoside (pyran type) OH H H 10 Quercetin-3-O -glucuronide Miquelianin 478.40 OH OH H Glucuronide OH H H >2000 11 Quercetin-3-O -robinobioside — 610.50 OH OH H Robinobioside OH H H >2000 12 Quercetin-3-O -rutinoside Rutin 610.50 OH OH H Rutinoside OH H H >2000 13 Quercetin-3-O -gentiobioside — 626.50 OH OH H Gentiobioside OH H H >2000
No. Flavonols Synonyms M.W. R3 R4 R5 R3 R5 R7 R8 IC50 (μ M) 14 Kaempferol-3-O -rhamnoside Afzelin 432.40 H OH H Rhamnoside OH H H 15 Kaempferol-3-O -galactoside Trifolin 448.40 H OH H Galactoside OH H H 16 Kaempferol-3-O -glucoside Astragalin 448.40 H OH H Glucoside OH H H 17 Kaempferol-3-O -rutinoside Nicotiflorin 594.50 H OH H Rutinoside OH H H >2000 18 Kaempferol-3,7-dirhamnoside Kaempferitrin 578.50 H OH H Rhamnoside OH Rhamnoside H >2000 19 Isorhamnetin-3-O -glucoside — 478.40 OCH3 OH H Glucoside OH H H >2000 20 Isorhamnetin-3-O -rutinoside Narcissoside 624.50 OCH3 OH H Rutinoside OH H H >2000 21 Myricetin — 318.24 OH OH OH H OH H H 22 Quercetin — 302.24 OH OH H H OH H H 23 Kaempferol — 286.24 H OH H H OH H H 24 Fisetin — 286.24 OH OH H H H H H 25 Herbacetin — 302.24 H OH H H OH H OH 26 Isorhamnetin — 316.26 OCH3 OH H H OH H H Acarbose (positive control)
