Long Noncoding RNA SCIRT Promotes HUVEC Angiogenesis via Stabilizing VEGFA mRNA Induced by Hypoxia

<div>HR promotes HUVEC angiogenesis with the marker VEGFA upregulated. (a) Representative images of the tube formation assay (scale bar, 100 <i>μ</i>m). (b) Representative images of the wound healing assay. (c) Representative images of transwell migration assay. (d) Protein levels of VEGFA in NC and HR conditions using western blot analysis. (e) Quantitative analysis of (d). The data showed that HR treatment induced the tube formation and promoted the migration of HUVECs. The ratio of invaded cells in the HR group was significantly higher than that in the NC group. VEGFA protein level is increased in the HR group compared with the NC group in HUVECs. (e) Quantitative analysis of (d). 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Long Noncoding RNA SCIRT Promotes HUVEC Angiogenesis via Stabilizing VEGFA mRNA Induced by Hypoxia 