Amelioration of Radiation-Induced Cell Death in Neuro2a Cells by Neutralizing Oxidative Stress and Reducing Mitochondrial Dysfunction Using N-Acetyl-L-Tryptophan

Figure 3

Estimation of radioprotective properties of L-NAT against ionizing radiation in Neuro2a cells using colony-forming units (CFU) assay. (a, b) Ionizing radiation dose response curve of Neuro2a cells at different radiation doses (2-7 Gy) was established. (c, d) The radioprotective effectiveness of L-NAT in irradiated Neuro2a cells was calculated at indicated radiation dose (5 Gy: LD₅₀). Statistical significance was calculated using one-way ANOVA with Turkey and the p-value presented as p <0.05; p <0.01; p <0.001 with respect to irradiated control. ^#p <0.001with respect to control.

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