Amelioration of Radiation-Induced Cell Death in Neuro2a Cells by Neutralizing Oxidative Stress and Reducing Mitochondrial Dysfunction Using N-Acetyl-L-Tryptophan

Figure 5

Protective influence of L-NAT pretreatment on radiation-induced DNA damage in Neuro2a cells. (a) Microscopic examination of radiation-induced DNA damage and its prevention by L-NAT pretreatment. (b) The effect of L-NAT (0.01-0.08 μg/ml) pretreatment on radiation-induced DNA damage in Neuro2a cells was investigated using the comet assay. Values were expressed as mean ± SEM, where p-value presented as p <0.05; p <0.01; p <0.001 with respect to irradiated control. ^#p <0.001 with respect to control.

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