Amelioration of Radiation-Induced Cell Death in Neuro2a Cells by Neutralizing Oxidative Stress and Reducing Mitochondrial Dysfunction Using N-Acetyl-L-Tryptophan

Figure 8

Effect of L-NAT pretreatment on mitochondrial membrane potential stabilization in irradiated Neuro2a cells. Ionizing radiation-induced depolarization of the mitochondrial membrane potential and L-NAT pretreatment help to stabilize mitochondrial membrane potential in irradiated Neuro2a cells. Error bars are mean ± SEM of triplicate measurement (n =3). Statistical significance was determined and p-value presented as p <0.05; p <0.01; p <0.001 with respect to irradiated control, ^#p <0.001with respect to control.