Dimethyl Sulfoxide Attenuates Radiation-Induced Testicular Injury through Facilitating DNA Double-Strand Break Repair

Figure 1

DMSO alleviates radiation-induced testicular injury and enhances seminiferous epithelium regeneration after irradiation. (a) The image of harvested testis and (b) the calculated testis index at 60 d post-IR. (c) Representative images of the H&E- and MVH- (DDX4) stained testis at the indicated days post-IR. . (d, e) Quantitative analysis of the diameter and the epithelial thickness of seminiferous tubules at various time points post-IR. Error bars indicate (). , , and . Student’s -tests were used to determine statistical significance in (a), (d), and (e).

(a)

(b)

(c)

(d)

(e)