MiR-9-5p Inhibits the MMP⁺-Induced Neuron Apoptosis through Regulating SCRIB/β-Catenin Signaling in Parkinson’s Disease

Figure 1

MPTP induced the apoptosis of dopaminergic neurons MN9D. (a, b) The apoptosis rate of MN9D cells in the mmp⁺ group was higher than that in the control group (). (c, d) The expression of cleaved-caspase 3 was higher in the mmp⁺ group than in the control group, and the expression of bcl-2 was lower (). (e, f) The expression of cleaved-caspase 3 was higher in PD mice (). The expression of TH was lower . (g) The expression of mmu-miR-9-5p was decreased in the mmp⁺ group than in the control group (). Scale bar: 100 μm.

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