MiR-9-5p Inhibits the MMP⁺-Induced Neuron Apoptosis through Regulating SCRIB/β-Catenin Signaling in Parkinson’s Disease

Figure 2

mmu-miR-9-5p reversed the MPTP-induced apoptosis of dopaminergic neurons. (a) The expression of mmu-miR-9-5p was upregulated after transfected with mmu-miR-9-5p mimics (). (b, c) The apoptosis rate of MN9D cells was reduced in the mmu-miR-9-5p group than in the miR-control group (). (d, e) Western blot showed cleaved-caspase 3 was downregulated, and bcl-2 was upregulated (). The blank group stands for untreated normal cells, the miR-control group was transfected with negative control miRNAs, and the miR-9-5p group was transfected with mmu-miR-9-5p mimics.

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