Adipose-Derived Stem Cell-Incubated HA-Rich Sponge Matrix Implant Modulates Oxidative Stress to Enhance VEGF and TGF-β Secretions for Extracellular Matrix Reconstruction In Vivo

Figure 3

(a) View of cultured ASCs within two types of matrices under a fluorescence microscope. (A) and (D): The left column images were viewed under the white light. (B) and (E): The middle column images were viewed under the red fluorescence microscope. (C) and (F): The right column images were merged photographs of the first and second column ones (bar =100 μm). (b) Steady enhancements of the cell proliferation rates for the vehicle control and HA-L and HA-H matrices. ASCs showed higher values cultured in HA-H matrix than in the HA-L one within a 7-day period culture. (c) The DCFDA assay results presented that HA-H matrix decreased ROS production in oxidative stress property assay. The photo representing order sequence (G)–(L) was similar as part demonstration (A)–(F). Each value was represented as the (). The level of significance is designated as and .

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