Research Article
Assessing the Potential Value and Mechanism of Kaji-Ichigoside F1 on Arsenite-Induced Skin Cell Senescence
Figure 3
Kaji-ichigoside F1 can downregulate the ERK/CEBPB signaling pathway and regulate the balance between oxidation and antioxidation, alleviating arsenic-induced skin cell senescence. The in vitro results were based on 6 independent experiments. All data are presented as . . (a) The relative mRNA expression of genes related to the ERK/CEBPB signaling pathway. (b) The relative protein expression related to the ERK/CEBPB signaling pathway. (c) The relative mRNA expression of p21 and p16INK4a to cell cycle regulation. (d) The relative protein expression of p21 and p16INK4a to cell cycle regulation. (e) The concentration of SASP. (f) The cell cycle for each group. (g) The concentration of oxidative stress indicators. (h) The western blot for the indicators of the ERK/CEBPB signaling pathway. (i) The western blot for p21 and p16INK4a. (j) The cell cycle analysis of flow cytometry.
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