Research Article

Fibroblast Growth Factor 19 Improves LPS-Induced Lipid Disorder and Organ Injury by Regulating Metabolomic Characteristics in Mice

Figure 9

Working model for FGF19-mediated fatty acid profiles involved in LPS-induced organ injury and oxidative stress. IPA: ingenuity pathway analysis; FGF19: fibroblast growth factor 19; LPS: lipopolysaccharide; LA: linoleic acids; GLA: gamma linolenic acid; DGLA: dihomo-gamma linolenic acid; MDA: malondialdehyde; CAT: catalase; GPX: glutathione peroxidase; iNOS: inducible NO synthase; NRF2: nuclear factor erythroid 2-related factor 2; HO-1: hemeoxygenase-1.