Adaptation of the Oxygen Sensing System during Lung Development

Figure 4

Expression pattern of the oxygen sensing system genes stratified by cell type and developmental age of the mouse lung by scRNA-seq data analysis. (a–g) Relative gene expression of the HIF-PHD system at the indicated time points stratified by selected cell types in lung epithelium, endothelium, or mesenchyme. Developmental stage is indicated by postconception days (E) or postnatal days (P); adult: P64. The intrauterine period is indicated by the gray background color. EC: endothelial cell; AT1/2: alveolar type 1/2 cell; FB: fibroblast.