Review Article

The Role of N6-Methyladenosine in Inflammatory Diseases

Figure 4

Cancer is regulated by m6A and the inflammatory microenvironment. In (a) lung adenocarcinoma and (b) human liver cancer, m6A modification regulates the expression of the target inflammatory gene. (c) Microenvironment inside the cancer and (d) numerous cytokines, such as IL-1β and IL-6, modulate the inflammatory microenvironment to stimulate tumor growth and invasion. (e) m6A application and targeting therapy in cancer through the inflammatory microenvironment.