Research Article
LncRNA-XIST Promotes Proliferation and Migration in ox-LDL Stimulated Vascular Smooth Muscle Cells through miR-539-5p/SPP1 Axis
Figure 3
Effects of XIST on proliferation, migration, and invasion of ox-LDL- stimulated vascular smooth muscle cells. (a) RT-qPCR was used to detect the efficiency of knockdown XIST in VSMCs. (b) CCK-8 assay showed cell viability in different groups. (c) The expression of Ki67 and PCNA protein. (d)–(f) Wound-healing assay () and transwell assay () showed effects on VSMCs invasion and migration. (g) The expression of MMP-2 and MMP-9 protein detected by western blot analyses. , , #, ##.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |