LncRNA-XIST Promotes Proliferation and Migration in ox-LDL Stimulated Vascular Smooth Muscle Cells through miR-539-5p/SPP1 Axis

<div>Targeting the relationship between lncRNA -XIST and miR-539-5p. (a) The relationships of base complementary pairing between XIST and miRNAs were predicted by starbase. (b) The targeting relationship between XIST and miRNAs was determined by dual luciferase report assay. (c) The bar graph showed changes of miR-539-5p expression level after downregulating XIST expression in VSMCs. (d) VSMC expressing of XIST and miR-539-5p was conducted with Ago2/RISC immunoprecipitation by Pan-Ago2 antibody, and IgG was used as a negative control. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: LncRNA-XIST Promotes Proliferation and Migration in ox-LDL Stimulated Vascular Smooth Muscle Cells through miR-539-5p/SPP1 Axis 