Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory <i>α</i>7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm

<div>Lp(a) levels positively correlate with patient monocytic <i>α</i>7-nAChR levels and are implicated in inflammation-associated CAS. (a) Box and whisker plot of the differential serum Lp(a) levels in control subjects and patients with CAS. Spearman dots and regression line plots showing the correlation between serum Lp(a) levels and (b) hs-CRP levels, (c) IL-6 expression, or (d) monocytic <i>α</i>7-nAChR expression, in patients with CAS. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory <i>α</i>7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm 

Figure 1 | Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory α7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm 