Investigation of the Effects of Glabridin on the Proliferation, Apoptosis, and Migration of the Human Colon Cancer Cell Lines SW480 and SW620 and Its Mechanism Based on Reverse Virtual Screening and Proteomics

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Item</td><td class="align_center">Genes name</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">Upregulated</td><td class="align_center">CDK2, THRB, RARA, MAOB, RARG, CTSS, AKR1D1, MMP3, NOS2, ACHE, ABL1, MAOA, AKR1C2, PTPN1, MMP12, PPARG, MMP13, CA2, MAPK14, INS, SEC14L2, PARP1, CSNK2A1, MMP8, PNLIP, PDE3B, RORC, Epn1, PPARD, AKR1C1, PDE4D, AKR1B1, HSP90AB1, CES1, BACE1, LCK, SRC, PPIA, TNK2, PKIA, CD1D, TTPA, ESR1, CHEK1, RXRA, NMRK1, OAT, PCTP, DCK, HMOX1, PIM1, KDR, C3, TGFBR1, GSR, RBP4, F10, REN, BRAF, MPO, DCXR, CD40LG, CASP7, FKBP1A</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>The targets screened by GBN were consistent with the upregulated protein in colorectal cancer cells.</div>

Oxidative Medicine and Cellular Longevity

tab5

Table 5

Table 5: Investigation of the Effects of Glabridin on the Proliferation, Apoptosis, and Migration of the Human Colon Cancer Cell Lines SW480 and SW620 and Its Mechanism Based on Reverse Virtual Screening and Proteomics 

Table 5 | Investigation of the Effects of Glabridin on the Proliferation, Apoptosis, and Migration of the Human Colon Cancer Cell Lines SW480 and SW620 and Its Mechanism Based on Reverse Virtual Screening and Proteomics 