Oxidative Stress Response Biomarkers of Ovarian Cancer Based on Single-Cell and Bulk RNA Sequencing

Figure 9

The RS model predicts the treatment outcomes of patients with OV. (a–h) The difference in the distribution of IC₅₀ values of eight chemotherapeutic drugs between the high-risk and low-risk groups. Red represents the high-risk group, and blue represents the low-risk group. (i) The heat map shows the correlation between the expression of model genes and the IC₅₀ values of chemotherapeutic drugs. The color of the dot represents the high and low correlation; represents the significance. (j) Histogram shows the cumulative distribution of immunotherapy response in patients in the high-risk and low-risk groups. (k) The violin diagram shows the distribution of RS in different immunotherapy response groups; the value is the significant difference in response between the two groups. Based on the effectiveness of immunotherapy, it is divided into complete response (CR), partial response (PR), stable disease (SD), or progressive disease (PD).

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