Protective Effect of Electroacupuncture on the Barrier Function of Intestinal Injury in Endotoxemia through HO-1/PINK1 Pathway-Mediated Mitochondrial Dynamics Regulation

Figure 5

Effect of EA on ROS production, ATP content, OCR, and DAO levels in the LPS-exposed wild-type (a, b, c, and d) and PINK1-knockout mice (e, f, g, and h). LPS: lipopolysaccharide, EA + AP: electroacupuncture (EA) on acupoint (AP), hemin: a substrate and inducer of HO-1, ZnPP: zinc protoporphyrin IX, an inhibitor of HO-1, OCR: oxygen consumption rate, ROS: reactive oxygen species, DAO: diamine oxidase, and ATP: adenosine triphosphate. The mRNA and protein levels were compared using the paired sample -test. : significant difference compared with the control cells (). ^#: significant difference compared with the LPS-exposed cells ().

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