Long Noncoding RNA LINC00578 Inhibits Ferroptosis in Pancreatic Cancer via Regulating SLC7A11 Ubiquitination

<div>SLC7A11 knockdown reversed the effects of OE-LINC00578 on ferroptosis. (a) Colony formation assay showed that cell proliferation promotion in PATU8988 cells by OE-LINC00578 introduction was reversed by Si-SLC7A11. (b) Quantitative analysis showed that the promotion of cell proliferation in PATU8988 cells by OE-LINC00578 introduction was reversed by Si-SLC7A11 by the colony formation assay. (c) Si-LINC00578 significantly reversed the inhibition of MMP depolarization in PATU8988 cells by OE-LINC00578 introduction. (d) Quantitative analysis of MMP. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Long Noncoding RNA LINC00578 Inhibits Ferroptosis in Pancreatic Cancer via Regulating SLC7A11 Ubiquitination 