Baicalin Inhibits Airway Smooth Muscle Cells Proliferation through the RAS Signaling Pathway in Murine Asthmatic Airway Remodeling Model

<div>Baicalin inhibits ASMC proliferation and RAS signaling pathway activation. (a) mRNA expression of <i>α-Sma/Tgf-β1/Mmp9/Timp1/Fibronectin1</i> and <i>Vegf</i> was measured by qPCR. (b) Protein expression of <i>α</i>-SMA and VIMENTIN was measured by western blot. The relative density of each protein was calculated. (c) ASMC proliferation was detected by the EdU (DAB) test. (d) MTT assay was used to assess ASMC proliferation. (e) The expression of differential proteins in key branching pathway of ASMCs was detected by western blot. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Baicalin Inhibits Airway Smooth Muscle Cells Proliferation through the RAS Signaling Pathway in Murine Asthmatic Airway Remodeling Model 