Research Article

Psoraleae Fructus Ethanol Extract Induced Hepatotoxicity via Impaired Lipid Metabolism Caused by Disruption of Fatty Acid β-Oxidation

Figure 2

Metabolomic analysis of mice liver tissues after PEE administration. (a) PCA scores in positive and negative modes. (b) OPLS-DA scores in positive and negative modes. (c) Volcano plot. Red and blue dots indicate significantly increased and decreased proteins, respectively. , , and or < 0.5. (d) The heat map shows 92 metabolites that were substantially altered in the liver were clustered in the control and PEE group. The red and blue represent increased and decreased metabolite content, respectively. (e) The KEGG pathway classification of differential proteins in the PFE group.
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