Metabolomics Profiling of Age-Associated Metabolites in Malay Population
Table 2
Metabolites associated with gender.
Compound name
Ionization mode
Signal level in males (SD)
Signal level in females (SD)
Mean difference (m-f)
Effect size ()
value
4-Hydroxyphenyllactic acid (4HPLA)
—
3.35 (1.395)
2.05 (1.385)
1.25
0.90
7.1-18
Indole-3-lactic acid
—
2.55 (8.604)
1.85 (8.554)
7.44
0.87
4.1-17
N-Acetyl-L-carnosine
+
3.14 (2.254)
1.34 (2.244)
1.74
0.78
4.7-14
Testosterone sulfate
—
6.06 (2.826)
4.06 (2.816)
2.06
0.71
4.9-12
3-Phenyllactic acid
—
8.84 (4.114)
6.04 (4.084)
2.84
0.68
2.7-11
Cortisol
+
8.64 (3.544)
7.04 (3.524)
1.64
0.46
5.0-6
Propionylcarnitine
+
5.55 (1.945)
4.65 (1.935)
8.34
0.43
1.8--5
Carnitine
+
3.97 (9.546)
3.57 (9.496)
4.06
0.43
2.4-5
Oleamide
+
2.56 (2.586)
3.56 (2.566)
-1.06
-0.40
7.0-5
Docosahexaenoic acid ethyl ester (DHAEE)
+
3.35 (2.825)
2.25 (2.815)
1.15
0.39
9.6-5
Glycoursodeoxycholic acid
—
1.76 (1.406)
1.26 (1.396)
5.55
0.39
9.7-5
Gamma-Glu-Leu
—
3.75 (1.945)
2.95 (1.935)
7.54
0.39
1.0-4
Theophylline
—
2.25 (1.825)
1.65 (1.815)
6.34
0.35
5.2-4
Hippuric acid
+
1.65 (1.395)
1.25 (1.385)
4.24
0.31
2.0-3
Proline
+
1.27 (4.156)
1.17 (4.136)
1.36
0.31
2.0-3
Indole-3-acetic acid
+
2.55 (8.604)
1.85 (8.554)
2.34
0.31
2.1-3
Xanthine
—
3.25 (1.405)
2.85 (1.395)
4.14
0.30
3.1-3
N-Acetylornithine
+
1.75 (7.544)
1.45 (7.504)
2.24
0.29
3.4-3
Signal intensity adjusted for age (arbitrary unit); f: females; m: males; SD; standard deviation; positive value represents higher level in males, negative value represents higher level in females; compounds were sorted according to effect size.
